I have heard about using Benadryl to calm an anxious dog down, but now there is new evidence that Melatonin might work better in some dogs.  Dog owners who are interested in a natural treatment for behavioral problems should ask their veterinarian about melatonin for dogs. Melatonin is a neurohormone, and it can be used as a sedative. There is no specific formulation of melatonin for dogs. It’s manufactured in human formulation, and the FDA has not actually approved its use in dogs. Veterinarians often prescribe it for a number of different treatments in dogs. Melatonin does not require a prescription. The human formulation is sold under the brand name Melatonex®, and it can be found in generic form simply labeled as melatonin.
Many owners have successfully used melatonin for dogs that are anxious or display other behavior problems. It can help calm a dog that becomes frightened at loud noises, such as thunderstorms, fireworks, or other sounds. The medication is often prescribed for canines that suffer from separation anxiety, such as when their owner leaves the house to go to work. Some dogs become overly excited at night and begin pacing or otherwise become a nuisance while the household is trying to sleep. Melatonin often works to calm a dog down enough so that it can rest.
